MOLECULAR BIOLOGY OF BONES & TEETH

Mission The goal of the Molecular Biology program is to explore the mechanisms that control the transcription of matrix genes expressed in mineralizing tissue. A second objective of the program is to understand the function of matrix proteins produced by bones and teeth. These studies are carried out using a combination of gene cloning, engineering and gene transfer using transgenic mice and cultured cells derived from the skeleton. Project Small Leucine Rich Proteoglycan Expression and Function in the Skeleton Staff Marian Young, Ph.D., Chief Yanming Bi, Ph.D., Postdoctoral IRTA Tina Kilts, AAS, Biologist Midlred Embree IRTA (Interim-enrolled in U of S. Carolina dental school). Colette Inkson, Ph.D. Visiting Fellow. "Marian's Methods". Offered as a service to the Scientific Community  Amplifying Adenovirus Bone Marrow Stromal Culture Calvaria Prep Mouse In-Vivo Analysis Northern Blotting Plasmid Transformation RNA Stat-60 RT-PCR Stains All For Proteins Western Staining Western-gel